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. 2021 Jun 3;26(11):3389. doi: 10.3390/molecules26113389

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Schematic representation of examples of different pathways associated with anti-proliferative effects induced by cannabinoid receptor activation in breast cancer. Reprinted from Ref. [253] with permission from Elsevier. License Number: 5066110731347. Abbreviation: PKA (protein kinase A); cAMP (Cyclic adenosine monophosphate); MAPK (mitogen-activated protein kinase); Ras (rats sarcoma protein); Raf1 (proto-oncogene serine/threonine protein kinase); MEK (Mitogen-activated protein kinase); ERK (extracellular signal regulated kinase); PGE2 (prostaglandine E-2); TrK (tropomyosin receptor kinase); PRL (prolactin) COX-2 (cyclooxygenase-2); Cdk (cyclin-dependant kinase); Chk 1 (cell cycle checkpoint).