Table 3.
The association between hepatic steatosis index score and urinary phthalates levels (ug/L).
| Phthalate Metabolites | Crude | Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
| MEHHP | ||||||||
| Quartile 1 | 1 | <0.001 * | 1 | 0.008 * | 1 | 0.015 * | 1 | 0.019 * |
| Quartile 2 | 1.09 (0.85–1.40) | 0.482 | 1.09 (0.83–1.44) | 0.514 | 1.07 (0.81–1.42) | 0.594 | 1.05 (0.80–1.38) | 0.702 |
| Quartile 3 | 1.39 (1.14–1.71) | 0.001 | 1.40 (1.08–1.81) | 0.010 | 1.34 (1.02–1.76) | 0.030 | 1.33 (1.00–1.78) | 0.044 |
| Quartile 4 | 1.41 (1.12–1.77) | 0.003 | 1.43 (1.04–1.95) | 0.024 | 1.40 (1.02–1.93) | 0.035 | 1.39 (1.00–1.92) | 0.044 |
| MEOHP | ||||||||
| Quartile 1 | 1 | 0.069 * | 1 | 0.657 * | 1 | 0.784 * | 1 | 0.835 * |
| Quartile 2 | 1.10 (0.86–1.40) | 0.445 | 1.04 (0.80–1.35) | 0.751 | 1.03 (0.79–1.34) | 0.784 | 1.01 (0.77–1.31) | 0.929 |
| Quartile 3 | 1.12 (0.98–1.51) | 0.067 | 1.10 (0.83–1.46) | 0.480 | 1.07 (0.80–1.44) | 0.618 | 1.05 (0.77–1.43) | 0.732 |
| Quartile 4 | 1.19 (0.96–1.49) | 0.109 | 1.05 (0.78–1.42) | 0.723 | 1.03 (0.76–1.40) | 0.827 | 1.02 (0.74–1.39) | 0.888 |
| MECPP | ||||||||
| Quartile 1 | 1 | 0.020 * | 1 | 0.214 * | 1 | 0.267 * | 1 | 0.245 * |
| Quartile 2 | 1.07 (0.85–1.36) | 0.531 | 1.04 (0.80–1.35) | 0.729 | 1.03 (0.80–1.34) | 0.773 | 1.01 (0.77–1.31) | 0.935 |
| Quartile 3 | 1.28 (1.04–1.59) | 0.020 | 1.20 (0.91–1.58) | 0.179 | 1.17 (0.88–1.55) | 0.270 | 1.14 (0.85–1.54) | 0.365 |
| Quartile 4 | 1.26 (1.00–1.60) | 0.047 | 1.18 (0.86–1.62) | 0.287 | 1.17 (0.84–1.61) | 0.337 | 1.18 (0.85–1.65) | 0.311 |
| MBzP | ||||||||
| Quartile 1 | 1 | 0.533 * | 1 | 0.664 * | 1 | 0.710 * | 1 | 0.792 * |
| Quartile 2 | 1.08 (0.86–1.37) | 0.467 | 1.02 (0.80–1.30) | 0.853 | 1.07 (0.84–1.36) | 0.573 | 1.05 (0.82–1.34) | 0.673 |
| Quartile 3 | 1.14 (0.92–1.42) | 0.220 | 1.03 (0.80–1.32) | 0.711 | 1.08 (0.84–1.38) | 0.529 | 1.06 (0.82–1.35) | 0.641 |
| Quartile 4 | 1.06 (0.84–1.34) | 0.612 | 0.93 (0.70–1.23) | 0.626 | 0.94 (0.71–1.24) | 0.678 | 0.95 (0.72–1.26) | 0.769 |
| MnBP | ||||||||
| Quartile 1 | 1 | 0.860 * | 1 | 0.191 * | 1 | 0.304 * | 1 | 0.420 * |
| Quartile 2 | 1.17 (0.95–1.44) | 0.139 | 1.05 (0.83–1.34) | 0.630 | 1.08 (0.85–1.38) | 0.492 | 1.07 (0.83–1.37) | 0.571 |
| Quartile 3 | 1.08 (0.86–1.34) | 0.481 | 0.90 (0.68–1.18) | 0.449 | 0.93 (0.71–1.22) | 0.632 | 0.94 (0.72–1.23) | 0.685 |
| Quartile 4 | 1.05 (0.82–1.33) | 0.686 | 0.83 (0.60–1.15) | 0.279 | 0.87 (0.63–1.21) | 0.424 | 0.90 (0.64–1.25) | 0.540 |
OR: odds ratio; CI: confidence interval; MEHHP: mono (2-ehtyl-5-hydroxyhexyl) phthalate; MEOHP: mono (2-ethyl-5-oxohexyl) phthalate; MECPP: mono (2-ethyl-5-carboxypentyl) phthalate; MnBP: mono-n-butyl phthalate; MBzP: mono-benzyl phthalate. *: p values were shown the test of trend of odds. Crude: hepatic steatosis index, each type of phthalate metabolites. Model 1: Crude + age, sex, creatinine. Model 2: Model 1 + smoking, drinking, exercise, marital status, education, socioeconomic status. Model 3: Model 2 + hypertension, diabetes mellitus, hyperlipidemia.