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. 2021 Jun 4;13(11):2785. doi: 10.3390/cancers13112785

Table 2.

Predictors of a histologic combination with non-predominant but higher grade pattern.

Imaging
Parameters
Univariate Multivariate
OR 95% CI p Value OR 95% CI p Value
Low grade as the most-predominant and intermediate grade as the second most predominant pattern
Shape 2.28 1.05–4.97 0.038 1.58 0.65–3.85 0.316
Distribution (scattered) 1.97 0.87–4.44 0.103 NA
Distribution (mixed) 0.53 0.23–1.24 0.146 NA
Distribution (compact) Ref NA
Area 30 1.70 0.75–3.83 0.205 NA
VNC group (middle) 2.17 0.76–6.21 0.148 NA
VNC group (low) 10.29 3.99–26.49 <0.0001 6.15 1.72–21.95 0.005
VNC group (upper) Ref NA
Mean iodine 0.97 0.94–0.99 0.007 0.98 0.95–1.02 0.318
SUVmax 0.77 0.64–0.94 0.008 0.93 0.77–1.12 0.421
Intermediate grade as the most-predominant and high grade as the second most predominant pattern
Shape 0.38 0.18–0.79 0.010 0.63 0.26–1.50 0.298
Distribution (scattered) 0.60 0.13–2.81 0.521 NA
Distribution (mixed) 2.98 1.36–6.52 0.006 2.01 0.82–4.97 0.128
Distribution (compact) Ref NA
Area 30 0.48 0.23–1.03 0.060 NA
VNC group (middle) 0.25 0.09–0.63 0.004 0.47 0.16–1.38 0.170
VNC group (low) 0.05 0.01–0.38 0.004 0.10 0.01–0.83 0.033
VNC group (upper) Ref NA
Mean iodine 1.02 0.99–1.04 0.221 NA
SUVmax 1.22 1.12–1.34 <0.0001 1.14 1.02–1.27 0.017

Note. CI = confidence interval, NA = not available, Ref = reference. Bold font = p < 0.05.