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. 2021 Jun 4;22(11):6060. doi: 10.3390/ijms22116060

Figure 3.

Figure 3

Gene expression profiles of NN, PN and PP biopsies. RNA was extracted from NN, PN and PP tissue biopsies and subject to RT-PCR analysis. Results are presented as the fold change in gene expression/GAPDH compared to NN gene expression/GAPDH. Data sets were statistically analysed by ANOVA followed by Dunnett’s multiple comparison test comparing PP and PN samples with control (***) and PN with PP samples (##). N = 6 biopsies per patient *** p < 0.0001; ## p < 0.005; * (#) p < 0.01. The dotted line indicates a two-fold increase in gene expression considered biologically significant [25].