Table 2.

Transcription factors for ITGA6 or ITGB1.

Gene Symbol	Gene Name	Expression in ICC 1 Cancer Tissues (p-Value)	Correlation with ITGA6 (p-Value)	Correlation with ITGB1 (p-Value)	miR-29-3p Binding Site	Reference
SP1	Sp1 transcription factor	<0.01	<0.01	<0.01	+	[24,25]
CREB1	cAMP responsive element binding protein 1	<0.01	<0.01	<0.01	−	[25]
MAX	MYC associated factor X	<0.01	<0.01	0.011	−	[25]
FHL2	four and a half LIM domains 2	<0.01	<0.01	<0.01	−	[25]
RFX1	regulatory factor X, 1 (influences HLA class II expression)	<0.01	<0.01	<0.01	−	[25]
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	<0.01	<0.01	0.019	−	[25]
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	<0.01	N.S	<0.01	−	[25]
CUX1	cut-like homeobox 1	<0.01	<0.01	N.S	−	[25]
USF1	upstream transcription factor 1	<0.01	N.S	<0.01	−	[25]
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	<0.01	N.S	N.S	+	[25]
FOXM1	forkhead box M1	<0.01	N.S	N.S	−	[26]
SPI1	Spi-1 proto-oncogene	<0.05	N.S	N.S	−	[25]
MXI1	MAX interactor 1, dimerization protein	N.S 2	0.011	N.S	+	[25]
PAX6	paired box 6	N.S	<0.01	<0.01	−	[25]
ESR1	estrogen receptor 1	N.S	0.015	<0.01	−	[25]
MEF2A	myocyte enhancer factor 2A	N.S	<0.01	0.038	−	[25]
HOXD3	homeobox D3	N.S	0.012	N.S	−	[25]
MYC	MYC proto-oncogene, bHLH transcription factor	N.S	N.S	N.S	−	[25]

¹ Intrahepatic cholangiocarcinoma, ² No significant difference.