. 2021 Jun 4;10(11):2489. doi: 10.3390/jcm10112489

Table 4.

Correlation between 18F-FDG uptake and clinical and biological disease activity.

18F-FDG Uptake	Systemic Score		Systemic Score + Ferritin > 4000		Ferritin		CRP		White Blood Cells
18F-FDG Uptake	ρ	p-Value	ρ	p-Value	ρ	p-Value	ρ	p-Value	ρ	p-Value
Spleen SUV_max	0.440	0.128	0.566	0.049^$	0.688	0.017 ^$	0.236	0.413	0.001	0.996
Spleen/Liver ratio *	0.431	0.135	0.534	0.064	0.765	0.003 ^$	0.532	0.039 ^$	0.396	0.125
Bone marrow SUV_max	0.287	0.416	0.425	0.229	0.575	0.104	0.467	0.187	−0.133	0.706
Bone marrow/Liver ratio *	0.584	0.065	0.616	0.052	0.553	0.046 ^$	0.745	0.007 ^$	0.324	0.243
Lymph nodes SUV_max	0.017	0.939	0.109	0.618	0.101	0.629	−0.246	0.238	−0.109	0.600
Lymph nodes/Liver ratio *	0.446	0.108	0.593	0.032 ^$	0.437	0.115	0.120	0.666	−0.077	0.782

The data were assessed using the Spearman correlation test. ^$ bold font: statistically significant. * SUV_max divided by the liver SUV_max; ρ: Spearman’s rank correlation coefficient; 18F-FDG: 18F-Fluorodeoxyglucose; CRP: C-reactive protein; Systemic score (range: 1–12) proposed by Pouchot et al. [14] assigns one point for each of the following manifestations: fever, typical rash, pleuritis, pneumonia, pericarditis, hepatomegaly or abnormal liver function tests, splenomegaly, lymphadenopathy, leukocytosis > 15,000/mm³, sore throat, myalgia, and abdominal pain.