Table 2.
Dosimetric metrics of initial plan, predicted dose on daily anatomy and adaptive plan.
| Dosimetric Parameter | Adaptive Criterion | Initial Plan | Predicted Plan | Adaptive Plan | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | Median | Q1 | Q3 | Mean | Median | Q1 | Q3 | Mean | Median | Q1 | Q3 | ||
| CTV mean dose (Gy) | 34.3 | 34.3 | 33.8 | 34.7 | 33.8 * | 33.8 | 33.3 | 34.6 | 34.2 | 34.2 | 33.5 | 34.9 | |
| CTV V95% | >93% | 100.0 | 100.0 | 100.0 | 100.0 | 96.2 * | 98.4 | 94.9 | 99.6 | 99.8 | 100.0 | 100.0 | 100.0 |
| PTV mean dose (Gy) | 34.0 | 34.0 | 33.4 | 34.6 | 33.5 * | 33.5 | 32.9 | 34.4 | 34.0 | 33.9 | 33.4 | 34.7 | |
| PTV V95% | >90% | 99.0 | 98.9 | 98.2 | 99.9 | 92.3 * | 94.4 | 88.5 | 96.5 | 98.2 + | 98.4 | 97.8 | 99.5 |
| Bladder mean dose (Gy) | 20.7 | 22.6 | 15.2 | 25.0 | 21.1 | 21.9 | 17.7 | 24.9 | 22.6 | 23.3 | 19.9 | 25.5 | |
| Bladder Dmax (Gy) | <36.7 Gy | 35.8 | 35.5 | 35.4 | 35.7 | 36.4 * | 36.0 | 35.6 | 37.0 | 35.6 + | 35.4 | 35.1 | 35.7 |
| Bladder V32.5Gy (%) | <35% | 25.3 | 23.2 | 17.9 | 40.7 | 25.7 | 25.7 | 17.3 | 34.2 | 24.2 | 27.7 | 16.5 | 33.6 |
| Rectum mean dose (Gy) | 15.4 | 15.5 | 12.7 | 18.6 | 15.4 | 14.7 | 12.9 | 18.4 | 15.6 | 15.6 | 13.6 | 18.3 | |
| Rectum Dmax (Gy) | <36.7 Gy | 34.5 | 35.0 | 33.4 | 35.2 | 35.5 * | 35.2 | 34.5 | 36.2 | 34.1 | 34.2 | 33.5 | 34.7 |
| Rectum V27.5Gy (%) | <45% | 10.2 | 8.1 | 5.2 | 14.1 | 11.4 | 9.1 | 6.4 | 15.6 | 8.5 + | 7.2 | 4.4 | 11.0 |
| Rectum V32.5Gy (%) | <30% | 3.1 | 1.4 | 0.2 | 5.3 | 4.9 * | 2.3 | 0.8 | 9.0 | 1.3 + | 0.4 | 0.1 | 1.1 |
| Rectal wall mean dose (Gy) | 15.6 | 15.3 | 12.7 | 18.7 | 15.3 | 14.6 | 12.7 | 18.3 | 15.7 | 15.8 | 13.5 | 18.2 | |
| Rectal wall V24Gy (%) | <50% | 19.9 | 20.7 | 13.8 | 24.1 | 19.4 | 18.2 | 15.2 | 24.5 | 19.5 | 19.0 | 13.4 | 23.9 |
(* p <0.05 between initial and predicted plan doses, + p < 0.05 between initial and adaptive plan doses.)