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. 2021 Jun 9;14:2413–2420. doi: 10.2147/IJGM.S302251

Table 3.

Spearman Correlation Matrix for the Studied Biomarkers and Clinical Characteristics

Osteopontin Osteocalcin Osteoprotegerin FGF23 Calcium Score
Bone-related markers
 Osteopontin 1 0.57** 0.56** 0.49** 0.32*
 Osteocalcin 0.57** 1 0.55** 0.74** −0.16
 Osteoprotegerin 0.57** 0.55** 1 0.59** 0.57**
 FGF23 0.49** 0.74** 0.59** 1 0.20
Imaging marker
 Calcium score 0.32* −0.16 0.57** 0.20 1
Clinical characteristics
 age 0.14821 −0.15 0.42** −0.14 0.62**
 eGFR −0.61** −0.78** −0.68** −0.81** −0.02
 CRP 0,21 0.17882 0.33* 0.20 0.19
 Procalcitonin 0,20 0.54** 0.36* 0.65** 0.03
 pH 0,07 0.34* 0.33* 0.55** 0.02
 Total protein −0.10 −0.27* −0.38* −0.35* −0.05
 Albumin 0.01 0.22 −0.31* 0.18 −0.21
 Ionized calcium −0.14 −0.43* −0.50** −0.49** −0.19
 Total calcium −0.26* −0.26 −0.46** −0.16 −0.31*
 Phosphorus 0.20 0.66** 0.37* 0.75** 0.04
 Parathyroid hormone 0.20 0.76** 0.26* 0.69** −0.03
 Vitamin D −0.14 −0.16 −0.11 −0.18 0.25

Notes: Correlation coefficients are presented (*Indicates coefficients significant at alpha = 0.05 and **Indicates coefficients significant at Bonferroni corrected alpha =0.0029).

Abbreviations: CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; FGF, fibroblast growth factor.