Table 3.
Spearman Correlation Matrix for the Studied Biomarkers and Clinical Characteristics
| Osteopontin | Osteocalcin | Osteoprotegerin | FGF23 | Calcium Score | |
|---|---|---|---|---|---|
| Bone-related markers | |||||
| Osteopontin | 1 | 0.57** | 0.56** | 0.49** | 0.32* |
| Osteocalcin | 0.57** | 1 | 0.55** | 0.74** | −0.16 |
| Osteoprotegerin | 0.57** | 0.55** | 1 | 0.59** | 0.57** |
| FGF23 | 0.49** | 0.74** | 0.59** | 1 | 0.20 |
| Imaging marker | |||||
| Calcium score | 0.32* | −0.16 | 0.57** | 0.20 | 1 |
| Clinical characteristics | |||||
| age | 0.14821 | −0.15 | 0.42** | −0.14 | 0.62** |
| eGFR | −0.61** | −0.78** | −0.68** | −0.81** | −0.02 |
| CRP | 0,21 | 0.17882 | 0.33* | 0.20 | 0.19 |
| Procalcitonin | 0,20 | 0.54** | 0.36* | 0.65** | 0.03 |
| pH | 0,07 | 0.34* | 0.33* | 0.55** | 0.02 |
| Total protein | −0.10 | −0.27* | −0.38* | −0.35* | −0.05 |
| Albumin | 0.01 | 0.22 | −0.31* | 0.18 | −0.21 |
| Ionized calcium | −0.14 | −0.43* | −0.50** | −0.49** | −0.19 |
| Total calcium | −0.26* | −0.26 | −0.46** | −0.16 | −0.31* |
| Phosphorus | 0.20 | 0.66** | 0.37* | 0.75** | 0.04 |
| Parathyroid hormone | 0.20 | 0.76** | 0.26* | 0.69** | −0.03 |
| Vitamin D | −0.14 | −0.16 | −0.11 | −0.18 | 0.25 |
Notes: Correlation coefficients are presented (*Indicates coefficients significant at alpha = 0.05 and **Indicates coefficients significant at Bonferroni corrected alpha =0.0029).
Abbreviations: CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; FGF, fibroblast growth factor.