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. 2021 Jun 13;92:109–128. doi: 10.1016/j.nutres.2021.05.008

Fig. 4.

Fig 4

The detailed molecular mechanism followed by Cu in the respiratory epithelium to escape from COVID-19 infection. The cellular entry of SARS-CoV-2 virus induces NF-κB, an inducible transcription factor which is responsible for inflammation by stimulating the proinflammatory genes. Conversely, Cu may prompt a number of mechanistic cascades to obstruct SARS-CoV-2-induced inflammatory events.