Table 4.

Association of eGFR variability with individual components of the composite CVD outcome

	Continuous Per SD increase = 0.06 HR (95% CI)
	Heart Failure	CVD death	MI	MI (silent)	Stroke	ACS	Cancer related deaths	Other deaths (non-cardiac, non-stroke, accident, unclassifiable)
# EVENTS	89	43	98	26	84	30	57	54
Model*	1.03 (0.85, 1.25)	1.10 (0.83, 1.47)	0.96 (0.77, 1.19)	1.29 (0.97, 1.70)	1.10 (0.90, 1.35)	0.86 (0.56, 1.32)	1.35 (1.13, 1.60)	1.35 (1.13, 1.63)

^*adjusted for age, sex, race, randomized arm, baseline history of CVD, history of heart failure, current smoking status, BMI, LDL, total cholesterol, ACR (baseline), eGFR (18 m), systolic blood pressure (18m), diastolic blood pressure (18m), ACEI/ARB (18m), diuretics (18m), calcium channel blocker (18m) and fasting status.

Abbreviations: CVD, cardiovascular disease; BMI, body mass index; LDL, low density lipoprotein; ACR, albumin creatinine ratio; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; MI, myocardial infarction; ACS, acute coronary syndrome.