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. 2021 May 31;8:683357. doi: 10.3389/fmed.2021.683357

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Copyright © 2021 Farkh, Ellouze, Gounelle, Sad Houari, Duchemin, Proulle, Fontenay, Delavenne and Jourdi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of DOAC Filter on LA testing in FXa inhibitor samples. dRVVT (A,C) and SCT (B,D) screen, confirm, and screen/confirm ratios in rivaroxaban (A,B, n = 38 and n = 36, respectively) and apixaban (C,D, n = 39) samples were calculated before (closed symbols) and after (open symbols) treatment with DOAC Filter. Two rivaroxaban samples could not be tested with SCT assays due to insufficient sample volume. Only samples having elevated screen ratio (i.e., ≥ 1.20) were subsequently analyzed using confirm assays. Dashed line corresponds to the cutoff value of 1.20. Horizontal lines represent median values.