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. 2021 May 31;8:675935. doi: 10.3389/fnut.2021.675935

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Copyright © 2021 Kalafati, Lenz, Ertaylan, Arts, Evelo, van Greevenbroek, Blaak, Adriaens and Kutmon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn diagram of the numbers of the upregulated (A) and downregulated (B) genes, for the M3 vs. M0 group comparison. Two models were used: adjusted for sex and (model 1) and additionally adjusted for differences in cell-type composition (model 2).