Table 1.
Classification criteria for the diagnosis of adult SpA and JSpA.
ASAS CRITERIA | ||||
---|---|---|---|---|
Axial SpA | Peripheral SpA | |||
For patients with ≥3 months back pain (with/without peripheral manifestations), aged <45 years | For patients with peripheral manifestations only | |||
Sacroiliitis on imaging plus ≥1 SpA feature | OR | HLA-B27 plus ≥2 other SpA features | Arthritis or enthesitis or dactylitis plus | |
SpA features: | ≥1 SpA feature: | |||
• Inflammatory back pain • Arthritis • Enthesitis (heel) • Uveitis • Dactylitis • Psoriasis • Crohn's disease/Ulcerative Colitis • Good response to NSAIDs • Family history of SpA • HLA-B27 • Elevated CRP |
• Uveitis • Psoriasis • Crohn's disease/ Ulcerative Colitis • Preceding infection • HLA-B27 • Sacroiliitis on imaging OR ≥2 other SpA features: • Arthritis • Enthesitis • Dactylitis • Inflammatory back pain ever • Family history of SpA |
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ILAR JIA CRITERIA | ||||
ERA | Juvenile onset psoriatic arthritis | |||
Arthritis AND enthesitis | Arthritis AND psoriasis | |||
OR | OR | |||
Arthritis OR Enthesitis plus ≥2 of: | Arthritis plus ≥2 of: | |||
• Current or past sacroiliac joint tenderness and/or inflammatory lumbosacral pain • HLA-B27 • Onset of arthritis in a male > 6 years old • Acute anterior uveitis • History of AS, ERA, sacroiliitis with inflammatory bowel disease, reactive arthritis or acute anterior uveitis in a first degree relative |
• Dactylitis • Nail pits or onycholysis • Family history of psoriasis in a first degree relative |
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Exclusions: | Exclusions: | |||
• Psoriasis or a history of psoriasis in the patient or a first degree relative • Presence of immunoglobulin M rheumatoid factor on at least two occasions 3 months apart • Presence of systemic JIA in the patient |
• Arthritis in an HLA-B27 positive male beginning after their 6th birthday • AS, ERA, sacroiliitis with inflammatory bowel disease, reactive arthritis or acute anterior uveitis, or a history of one of these in a first degree relative • Presence of immunoglobulin M rheumatoid factor on at least two occasions 3 months apart • Presence of systemic JIA in the patient |
ASAS, Assessment of SpA International Society; ILAR, International League of Associations for Rheumatology; JIA, juvenile idiopathic arthritis.