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. 2021 May 31;8:681621. doi: 10.3389/fmed.2021.681621

Table 1.

Classification criteria for the diagnosis of adult SpA and JSpA.

ASAS CRITERIA
Axial SpA Peripheral SpA
For patients with ≥3 months back pain (with/without peripheral manifestations), aged <45 years For patients with peripheral manifestations only
Sacroiliitis on imaging plus ≥1 SpA feature OR HLA-B27 plus ≥2 other SpA features Arthritis or enthesitis or dactylitis plus
SpA features: ≥1 SpA feature:

  • Inflammatory back pain
  • Arthritis
  • Enthesitis (heel)
  • Uveitis
  • Dactylitis
  • Psoriasis
  • Crohn's disease/Ulcerative Colitis
  • Good response to NSAIDs
  • Family history of SpA
  • HLA-B27
  • Elevated CRP

  • Uveitis
  • Psoriasis
  • Crohn's disease/ Ulcerative Colitis
  • Preceding infection
  • HLA-B27
  • Sacroiliitis on imaging
OR
≥2 other SpA features:
  • Arthritis
  • Enthesitis
  • Dactylitis
  • Inflammatory back pain ever
  • Family history of SpA
ILAR JIA CRITERIA
ERA Juvenile onset psoriatic arthritis
Arthritis AND enthesitis Arthritis AND psoriasis
OR OR
Arthritis OR Enthesitis plus ≥2 of: Arthritis plus ≥2 of:

  • Current or past sacroiliac joint tenderness and/or inflammatory lumbosacral pain
  • HLA-B27
  • Onset of arthritis in a male > 6 years old
  • Acute anterior uveitis
  • History of AS, ERA, sacroiliitis with inflammatory bowel disease, reactive arthritis or acute anterior uveitis in a first degree relative

  • Dactylitis
  • Nail pits or onycholysis
  • Family history of psoriasis in a first degree relative
Exclusions: Exclusions:

  • Psoriasis or a history of psoriasis in the patient or a first degree relative
  • Presence of immunoglobulin M rheumatoid factor on at least two occasions 3 months apart
  • Presence of systemic JIA in the patient

  • Arthritis in an HLA-B27 positive male beginning after their 6th birthday
  • AS, ERA, sacroiliitis with inflammatory bowel disease, reactive arthritis or acute anterior uveitis, or a history of one of these in a first degree relative
  • Presence of immunoglobulin M rheumatoid factor on at least two occasions 3 months apart
  • Presence of systemic JIA in the patient

ASAS, Assessment of SpA International Society; ILAR, International League of Associations for Rheumatology; JIA, juvenile idiopathic arthritis.