Figure 2.

The influence of Chlorella consumption on the gut microbiome and metabolome profiles was not larger than that of control supplement consumption. (A,C) Box plot representing the distribution of Spearman coefficient distance for the gut microbiome (A) and metabolome profiles (C) among samples from different subjects at the first timepoint (inter) and the distance between samples from the same subject (intra). (B,D) The boxplots show the microbiome profile distance (B) and metabolome profile distance (D) within an individual between the labelled timepoints. A significant difference test was performed during the same intake period (T1–T2 and C1–C2, or T1–T3 and C1–C3), but no significant difference was detected (Wilcoxon signed-rank test).