Table 2.

Chlorella intake increases dicarboxylic acid levels in faeces.

	p-valuea	p-valueb	C1c	C3c	T1c	T3c	Brite1	Brite2	Brite3
Azelaic acid	0.0003	0.0045	0.0067 (0.0049)	0.0062 (0.0046)	0.0051 (0.0027)	0.0078 (0.0049)	Fatty acyls	Fatty Acids and Conjugates	Dicarboxylic acids
6-Hydroxyhexanoic acid	0.0038	0.0005	0.0058 (0.0090)	0.0040 (0.0068)	0.0050 (0.0068)	0.0084 (0.0094)	Fatty acyls	Fatty Acids and Conjugates	Hydroxy fatty acids
Suberic acid	0.0040	0.0003	0.0031 (0.0016)	0.0024 (0.0011)	0.0024 (0.0007)	0.0036 (0.0018)	Organic acids	Carboxylic acids	Dicarboxylic acids
							Fatty acyls	Fatty Acids and Conjugates	Dicarboxylic acids
Sebacic acid	0.0048	0.0064	0.0015 (0.0009)	0.0012 (0.0010)	0.0010 (0.0008)	0.0019 (0.0013)	Fatty acyls	Fatty Acids and Conjugates	Dicarboxylic acids
4-Oxohexanoic acid	0.0051	0.0438	0.0013 (0.0007)	0.0013 (0.0005)	0.0011 (0.0007)	0.0016 (0.0006)	N.A.	N.A.	N.A.
Hordenine	0.0076	0.0151	0.0002 (0.0002)	0.0002 (0.0002)	0.0002 (0.0002)	0.0001 (0.0002)	Alkaloids	Alkaloids derived from tyrosine	Tyramine derivatives
Heptanoic acid	0.0123	0.0112	0.0052 (0.0122)	0.0042 (0.0083)	0.0046 (0.0109)	0.0066 (0.0108)	Organic acids	Carboxylic acids	Monocarboxylic acids
							Fatty acyls	Fatty Acids and Conjugates	Straight chain fatty acids
Anserine_divalent	0.0158	0.009	0.0014 (0.0020)	0.0016 (0.0016)	0.0020 (0.0020)	0.0009 (0.0009)	N.A.	N.A.	N.A.
Homocarnosine	0.0198	0.0051	0.0003 (0.0003)	0.0004 (0.0004)	0.0004 (0.0003)	0.0002 (0.0003)	N.A.	N.A.	N.A.
Dodecanedioic acid	0.0333	0.0333	0.0105 (0.0169)	0.0064 (0.0065)	0.0049 (0.0039)	0.0140 (0.0233)	Fatty acyls	Fatty Acids and Conjugates	Dicarboxylic acids

Classification of significantly enriched faecal metabolites upon Chlorella intake based on the KEGG BRITE database (p < 0.05 in both comparisons between C1–C3 and T1–T3 and between T1 and T3).

^aValues indicate Wilcoxon signed-rank test result between T1 and T3.

^bValues indicate Wilcoxon signed-rank test result between C1–C3 and T1–T3.

^cValues are given as the mean (S.D.).