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. 2021 May 7;22(6):71–82. doi: 10.1002/acm2.13254

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© 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 3 — The final results of a single optimization run using the AFI approach. Shown are the five PTVs (solid color) of each multi‐target plan and the IDC50% (transparent yellow). All plans use a single isocenter, two couch angles, and six arc delivery to treat all PTVs simultaneously. The AP and right lateral setup field is shown for scale. (a) Five spherical shaped PTVs of widely varying volumes, 0.19 cm³ to 8 cm³. (b) Five irregularly shaped PTVs of volumes 0.73 cm³ to 1.67 cm³. (c) Five jack shaped PTVs of volumes 1.11–1.83 cm³. Notice there are no extraneous IDC50% volumes far from the PTVs, and any given individual IDC50% is highly conformal and of comparable shape to its associated PTV.