Table 3.
Z-score outliers for the DTI metrics of fractional anisotropy (FA), axial diffusivity (AD) and radial diffusivity (RD).
| Region of Interest | Fractional anisotropy (FA) | Axial diffusivity (AD) | Radial diffusivity (RD) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Control Mean | Control SD | No. Outliers (± 2σ) | No. Outliers (± 3σ) | Control Mean | Control SD | No. Outliers (± 2σ) | No. Outliers (± 3σ) | Control Mean | Control SD | No. Outliers (± 2σ) | No. Outliers (± 3σ) | |
| Acoustic Radiation Left | 0.2844 | 0.0257 | 5 | 0 | 1.16 × 10−3 | 4.15 × 10−5 | 1 | 0 | 7.68 × 10−4 | 4.98 × 10−5 | 4 | 0 |
| Acoustic Radiation Right | 0.2724 | 0.0257 | 4 | 0 | 1.17 × 10−3 | 3.60 × 10−5 | 6 | 1 | — | — | — | — |
| Cingulate Gyrus Left | 0.3609 | 0.0379 | 2 | 0 | 1.12 × 10−3 | 6.49 × 10−5 | 0 | 0 | 6.47 × 10−4 | 3.71 × 10−5 | 5 | 0 |
| Cingulate Gyrus Right | 0.3095 | 0.0485 | 1 | 0 | 1.07 × 10−3 | 6.25 × 10−5 | 0 | 0 | 6.76 × 10−4 | 4.08 × 10−5 | 5 | 0 |
| Cingulum Left | 0.3455 | 0.0407 | 3 | 0 | — | — | — | — | 6.74 × 10−4 | 4.31 × 10−5 | 0 | 0 |
| Cingulum Right | 0.358 | 0.0513 | 0 | 0 | — | — | — | — | 6.59 × 10−4 | 4.59 × 10−5 | 0 | 0 |
| Corpus Callosum | 0.4076 | 0.0319 | 0 | 0 | — | — | — | — | — | — | — | — |
| Corticospinal Tract Left | 0.4713 | 0.0229 | 3 | 2 | 1.32 × 10−3 | 6.14 × 10−5 | 3 | 0 | 6.52 × 10−4 | 6.32 × 10−5 | 6 | 0 |
| Corticospinal Tract Right | 0.4652 | 0.0219 | 5 | 1 | 1.32 × 10−3 | 6.11 × 10−5 | 10 | 1 | 6.52 × 10−4 | 5.40 × 10−5 | 10 | 2 |
| Forceps Major | 0.3871 | 0.0512 | 0 | 0 | 1.34 × 10−3 | 9.49 × 10−5 | 3 | 0 | 7.29 × 10−4 | 7.91 × 10−5 | 1 | 0 |
| Forceps Minor | 0.377 | 0.0265 | 3 | 1 | 1.22 × 10−3 | 4.73 × 10−5 | 1 | 0 | 6.90 × 10−4 | 3.60 × 10−5 | 4 | 1 |
| Fornix | 0.2999 | 0.0415 | 2 | 0 | 1.68 × 10−3 | 1.66 × 10−4 | 2 | 0 | 1.09 × 10−3 | 1.85 × 10−4 | 1 | 0 |
| Hippocampus Left | 0.2652 | 0.0405 | 2 | 0 | 1.12 × 10−3 | 5.31 × 10−5 | 0 | 0 | 7.60 × 10−4 | 6.24 × 10−5 | 0 | 0 |
| Hippocampus Right | 0.2764 | 0.0399 | 1 | 0 | 1.13 × 10−3 | 4.88 × 10−5 | 4 | 0 | 7.60 × 10−4 | 6.22 × 10−5 | 1 | 0 |
| Inferior Fronto-occipital Fasciculus Left | 0.3978 | 0.0207 | 12 | 2 | 1.20 × 10−3 | 6.05 × 10−5 | 0 | 0 | 6.53 × 10−4 | 3.27 × 10−5 | 0 | 0 |
| Inferior Fronto-occipital Fasciculus Right | 0.3945 | 0.0255 | 5 | 0 | 1.21 × 10−3 | 5.54 × 10−5 | 0 | 0 | 6.56 × 10−4 | 4.56 × 10−5 | 0 | 0 |
| Inferior Longitudinal Fasciculus Left | 0.3517 | 0.023 | 12 | 1 | 1.17 × 10−3 | 6.54 × 10−5 | 0 | 0 | 6.88 × 10−4 | 3.58 × 10−5 | 0 | 0 |
| Inferior Longitudinal Fasciculus Right | 0.36 | 0.0282 | 6 | 1 | 1.15 × 10−3 | 5.79 × 10−5 | 0 | 0 | 6.72 × 10−4 | 4.26 × 10−5 | 0 | 0 |
| Optic Radiation Left | 0.2975 | 0.0157 | 1 | 0 | 1.15 × 10−3 | 4.88 × 10−5 | 1 | 0 | 7.28 × 10−4 | 3.29 × 10−5 | 2 | 0 |
| Optic Radiation Right | 0.3092 | 0.0192 | 2 | 0 | 1.14 × 10−3 | 4.27 × 10−5 | 1 | 0 | 7.09 × 10−4 | 3.34 × 10−5 | 0 | 0 |
| Superior Longitudinal Fasciculus Left | 0.3337 | 0.0178 | 11 | 4 | 1.10 × 10−3 | 4.41 × 10−5 | 0 | 0 | 6.78 × 10−4 | 2.85 × 10−5 | 1 | 0 |
| Superior Longitudinal Fasciculus Right | 0.3482 | 0.0185 | 17 | 8 | 1.10 × 10−3 | 4.12 × 10−5 | 0 | 0 | 6.62 × 10−4 | 3.12 × 10−5 | 1 | 0 |
| Uncinate Fasciculus Left | 0.3786 | 0.0322 | 7 | 1 | — | — | — | — | 6.78 × 10−4 | 3.83 × 10−5 | 10 | 3 |
| Uncinate Fasciculus Right | 0.3534 | 0.0401 | 4 | 0 | — | — | — | — | 7.15 × 10−4 | 5.55 × 10−5 | 4 | 0 |
An outlier from the Z-distribution implies that area of the brain to be injured. Note: ROIs that failed the normality test and therefore, could not be used for analysis are signified by “—“.