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. 2021 May 31;9:625726. doi: 10.3389/fped.2021.625726

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Copyright © 2021 Frost, Suriano, Aye, Leeson and Lewandowski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn diagram showing the unique cardiac and vascular changes in offspring born preterm to normotensive and hypertensive pregnancies. All characteristics described differ from those born at term to normotensive pregnancies. Changes shown in the middle of the Venn diagram are not distinguishable between the offspring born preterm to normotensive and hypertensive pregnancies. Changes on the left are additional changes seen in the offspring born preterm to hypertensive pregnancies, and those on the right are additional changes seen in the offspring born preterm to normotensive pregnancies. Characteristics on the left that are italicized and not in bold are inconclusive and require further investigation. ECFC, endothelial colony-forming cell; HUVEC, human umbilical vein endothelial cell; LV, left ventricle; RV, right ventricle.