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. 2021 May 31;12:599664. doi: 10.3389/fmicb.2021.599664

Figure 2.

Figure 2

Beta diversity of e-cigarette users and NSNV controls. (A,B) Principal coordinates plots of beta-diversity based on (A) Bray Curtis and (B) Jaccard indices from buccal and saliva samples collected from e-cigarette users and NSNV controls. Color denotes e-cigarette status (E-cigarette users, orange; NSNV controls, blue). Ellipses are drawn at 95% CI for e-cigarette status. Significance determined by ANOSIM with 999 permutations for e-cigarette status and denoted in the upper corner of each panel, *p < 0.05. (C,D) Violin plots showing the distribution of (C) Bray Curtis and (D) Jaccard indices within each cohort (e-cigarette users and NSNV controls) from buccal and saliva samples. Significant difference (p < 0.05) determined by an unpaired two-sample Wilcoxon test.