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. 2021 May 31;12:599664. doi: 10.3389/fmicb.2021.599664

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Copyright © 2021 Chopyk, Bojanowski, Shin, Moshensky, Fuentes, Bonde, Chuki, Pride and Crotty Alexander.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Change in alpha diversity in e-cigarette users at each visit. (A,B) Line graph showing the number of Observed OTUs from (A) buccal and (B) saliva samples collected from e-cigarette users before and after reduction in vaping. The Observed OTUs are shown on the y-axis and the time before and after reduction in vaping on the x-axis. (C) Bar plots showing the aggregate data (±SE) before and after reduction in product use for buccal and saliva samples. Significance (p < 0.05) determined by a paired two-sample Wilcoxon test.