Table 4.
Results from the univariate analysis of clinical data of two groups.
Variable | Good-prognosis (n = 117) | Poor-prognosis (n = 68) | Statistical value | p |
---|---|---|---|---|
Age (y) | 23 (14–32) | 29 (21–37) | −2.17 | 0.043† |
Clinical symptoms (n, %) | ||||
Seizures | 93 (75.0%) | 53 (86.9%) | 3.472 | 0.054 |
Mental behavioral disorders | 59 (47.6%) | 51 (83.6%) | 22.096 | 0.012* |
Memory deficit | 78 (62.9%) | 45 (73.8%) | 2.167 | 0.095 |
Movement disorder | 27 (21.8%) | 31 (50.8%) | 16.027 | 0.037* |
Disturbance of consciousness | 30 (24.2%) | 39 (63.9%) | 27.612 | <0.001* |
Central hypoventilation | 5 (4.0%) | 12 (19.7%) | 11.985 | 0.001* |
Complicated with tumors | 4 (3.2%) | 16 (26.2%) | 22.439 | <0.001* |
Admission to ICU | 3 (2.4%) | 10 (16.4%) | 12.221 | <0.001* |
CSF analysis | ||||
Increased level of protein | 37 (29.8%) | 20 (32.8%) | 0.167 | 0.736 |
Positive oligoclonal bands | 6 (4.8%) | 13 (21.3%) | 12.039 | 0.001* |
Serum analysis | ||||
Hyponatremia | 48 (38.7%) | 7 (11.5%) | 14.516 | 0.001* |
Abnormal thyroid function | 43 (34.7%) | 20 (32.8%) | 0.065 | 0.870 |
Abnormal brain MRI signal | 55 (44.4%) | 40 (65.6%) | 7.369 | 0.008* |
Abnormal EEG findings | 90 (72.6%) | 41 (67.2%) | 0.570 | 0.592 |
Immunotherapy (n, %) | ||||
Steroids | 27 (21.8%) | 6 (9.8%) | 3.976 | 0.065 |
IVIG | 4 (3.2%) | 3 (4.9%) | 0.322 | 0.686 |
Steroids + IVIG | 78 (62.9%) | 50 (82.0%) | 6.971 | 0.011* |
Second-line treatment | 14 (11.3%) | 12 (19.7%) | 2.378 | 0.176 |
Z-value in the Mann-Whitney U-test; *χ2,
p-value in Fisher's exact test.