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. 2021 May 31;12:677961. doi: 10.3389/fneur.2021.677961

Table 3.

Cox regression analysis of predictors for future MACEs.

Primary outcome characteristics Univariate Multivariate
Variable MACE Non-MACE p-value HR (95% CI) p-value OR (95% CI)
Age, years 53.5 ± 9.8 58.0 ± 12.5 0.044 0.927 (0.861–0.998) 0.238
Gender 6 (75.0) 113 (62.8) 0.184 6.613 (0.405–107.921)
HH grade 3–5 3 (37.5) 51 (28.3) 0.248 0.222 (0.017–2.862)
*FS 3–4 4 (50.0) 73 (40.6) 0.728 1.436 (0.185–11.13)
IVH involvement 5 (62.5) 101 (56.1) 0.518 1.818 (0.295–11.191)
Smoke 2 (25.0) 56 (31.1) 0.43 0.388 (0.037–4.079)
History of stroke 2 (25.0) 31 (17.2) 0.226 0.302 (0.043–2.098)
Hypertension 4 (50.0) 112 (62.2) 0.239 3.31 (0.449–24.361)
HR 82.9 ± 18.1 75.6 ± 13.5 0.405 1.027 (0.964–1.093)
SBP 159.9 ± 26.0 161.3 ± 24.2 0.634 1.008 (0.975–1.042)
Elevated cTnI 5 (62.5) 42 (23.3) 0.016 9.063 (1.487–55.209) 0.014 5.980 (1.428–25.407)
ih.MACE 5 (62.5) 49 (27.2) 0.064 4.528 (0.91–22.512) 0.064
ih.DCI/CI 1 (12.5) 33 (18.3) 0.246 0.236 (0.02–2.711)
ih.pneumonia 4 (50.0) 58 (32.2) 0.033 0.104 (0.013–0.837) 0.211
ih.DVT 4 (50.0) 52 (28.9) 0.512 0.521 (0.074–3.656) 0.622
*

FS, Fisher score; HR, admission heart rate; SBP, admission systolic blood pressure; cTnI, cardiac troponin I; ih.MACE, in hospitalization major adverse cardiac event; ih.DCI/CI, in hospitalization delayed cerebral ischemia/ cerebral infarction; ih.pneumonia, in hospitalization pneumonia; ih.DVT, in hospitalization deep venous thrombosis.