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. 2020 Sep 6;2020(9):CD012658. doi: 10.1002/14651858.CD012658.pub2

NCT03463252.

Study name Value of levonorgestrel‐releasing intrauterine system (LNG‐IUS) in the fertility‐preserving treatment of atypical endometrial hyperplasia and early endometrial carcinoma
Methods Randomised, parallel assignment
Participants 224 women with atypical endometrial hyperplasia or early endometrial carcinoma, fertility sparing treatment
Interventions 1. MPA
2. MPA + LNG‐IUS
3. LNG‐IUS
Outcomes Primary: pathological response rate (regression), pregnancy rate, live birth rate
Secondary: side effects rate
Starting date 1 April 2018
Contact information Professor Ying Zheng; 935398163@qq.com
Notes Clinicaltrials.gov NCT03463252