Table 5.

Association of Events After Visit 3 With HF Stages at That Visit Stratified by Median Age (58 y)

HF Stage †	Hazards Ratios for Events (95% CI)
	Clinical HF Events*		CVD Events*		CVD Death*		All‐Cause Death*
	Age ≤ Median (130/708)	Age ˃Median (152/913)	Age ≤ Median (201/760)	Age ˃Median (160/949)	Age ≤ Median (122/807)	Age ˃Median (58/975)	Age ≤ Median (376/807)	Age ˃Median (222/975)
A	Referent	Referent	Referent	Referent	Referent	Referent	Referent	Referent
B	1.9 (1.2–3.1)	1.6 (1.1–2.5)	1.4 (0.9–2.1)	1.5 (1.0–2.3)	2.2 (1.2–4.1)	1.8 (0.9–3.9)	1.6 (1.2–2.2)	1.3 (0.9–1.9)
C/D	…	…	3.0 (1.9–5.0)	1.7 (0.8–3.6)	7.4 (3.7–14.7)	7.0 (2.8–17.5)	3.5 (2.4–5.0)	2.9 (1.8–4.7)
P for interaction ‡	0.63		0.21		0.21		0.59

CVD indicates cardiovascular disease; HF, heart failure; and MI, myocardial infarction.

^*We provide the number of events for each outcome within each age category and the total number of participants.

^†HF stage A formed the referent group in all tests. We excluded prevalent MI in heart stage B (N=89).

^‡ P value for interaction of HF stage with median age.