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. 2021 Apr 29;10(9):e018062. doi: 10.1161/JAHA.120.018062

Figure 9. Vectors of linc01278 regulated the vascular smooth muscle cells marker genes in vitro.

Figure 9

A, Quantitative reverse transcription‐PCR showed linc01278 upexpression by vectors of linc01278. n=3. **: P<0.01; B, miR‐500b‐5p mimics increased miR‐500b‐5p. n=3. **: P<0.01. C, Vectors of linc01278 significantly increased vascular smooth muscle cells differentiation marker genes, whereas the effect of vectors of linc01278 could be remedied by transfection with miR‐500b‐5p mimics. n=3. *: P<0.05. D and E, Vectors of linc01278 significantly increased vascular smooth muscle cells differentiation marker genes as determined by Western blot analysis, whereas miR‐500b‐5p mimics reverse the vascular smooth muscle cells switching state by increasing expression of linc01278. n=3. *: P<0.05. PCR indicates polymerase chain reaction.