Figure 10. Role of si‐linc01278 in vascular smooth muscle cells proliferation and migration.

A and B, Scrape assay showed that the increased migration of human aortic vascular smooth muscle cells was stimulated by transfection with Si‐linc01278 and Si‐linc01278+miR‐500b‐5p inhibitor control, but the increased state was reversed by transfection with Si‐linc01278+miR‐500b‐5p inhibitor. C, Matrix metalloproteinase‐2 and matrix metalloproteinase‐9 were increased by quantitative reverse transcription‐PCR as transfection with Si‐linc01278. D, Western blot showed high expression of ki‐67 in vascular smooth muscle cells transfected with Si‐linc01278. E, The decreased linc01278 promoted vascular smooth muscle cells proliferation as measured by cell counting kit‐8 assay (n=10). *^,# P<0.05 vs 12 hours. PCR indicates polymerase chain reaction.