. 2021 Jun 3;22(2):827. doi: 10.3892/etm.2021.10259

Table II.

Comparison of initial ADC values in patients according to the stage of disease and MRI aspect.

				P-value
	Stage 1	Stage 2	Stage 3	(1 vs. 2 vs. 3)^b	(1 vs. 2)^c	(1 vs. 3)^c	(2 vs. 3)^c
ADC (mm²/sec)	0.289 (0.19-0.72)	1.162 (0.73-1.28)	0.867 (0.58-1.12)	0.037^a	0.033^a	0.041^a	0.661
				P-value
	Normal (N) marrow	Focal lesions (L)	Marrow infiltration (I)	(N vs. L vs. I)^b	(N vs. L)^c	(N vs. I)^c	(L vs. I)^c
ADC (mm²/sec)	0.307 (0.26-0.42)	1.010 (0.87-1.34)	1.123 (0.85-1.13)	<0.001^a	<0.001^a	0.001^a	0.585

^aDifferences between groups are significant at P<0.05 threshold;

^bKruskal-Wallis test;

^cMann-Whitney U post-hoc test, adjusted P-value for pairwise comparison with Bonferroni correction. ADC, apparent diffusion coefficient; MRI, magnetic resonance imaging. ADC values are according to the type of bone infiltration. Data are expressed as median and interquartile (Q1-Q3).