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. 2021 Jun 4;22(2):835. doi: 10.3892/etm.2021.10267

Figure 4.

Figure 4

ZFAS1-knockdown suppresses the excessive migration and invasion of VSMCs induced by ox-LDL. (A) Migration of VSMCs was determined by wound healing assay (scale bar, 100 µm). (B) Invasion of VSMCs was determined by Transwell chamber assay (scale bar, 100 µm). (C) Quantification of cell migration. (D) Quantification of cell invasion. The data are expressed as the mean ± SEM from three independent experiments. ***P<0.001 vs. Control; #P<0.05 and ##P<0.01 vs. ox-LDL + si-NC. ZFAS1, zinc finger antisense 1; ox-LDL, oxidized low-density lipoprotein; VSMCs, vascular smooth muscle cells; si, small interfering RNA; NC, negative control.