Table 1.
Clinical and biochemical characteristics of participants in two cohorts according to TG levels.
| LMUFAH | SAHODMU | |||||
|---|---|---|---|---|---|---|
| TG <1.7 mmol/L | TG ≥ 1.7 mmol/L | P | TG <1.7 mmol/L | TG ≥ 1.7 mmol/L | P | |
| N | 60 | 86 | 106 | 188 | ||
| TG, mmol/L | 1.13 (0.83–1.35) | 2.48 (2.03–3.20) | <0.0001 | 1.11 (0.88–1.42) | 2.68 (2.04–3.87) | <0.0001 |
| Age, years | 56.0 ± 11.2 | 55.0 ± 12.2 | 0.6047 | 62.2 ± 11.0 | 57.8 ± 12.7 | 0.0011 |
| Sex, male | 33 (55.0) | 48 (55.8) | 0.9224 | 62 (58.5) | 89 (47.3) | 0.0663 |
| Duration of diabetes, years | 5 (0–11) | 5 (0–10) | 0.8364 | 11 (4–17) | 8 (2–15) | 0.0754 |
| Body mass index, kg/m2 | 24.4 ± 3.4 | 26.3 ± 3.4 | 0.0016 | 26.6 ± 4.5 | 27.0 ± 3.5 | 0.3727 |
| Current smoking | 25 (41.7) | 33 (38.4) | 0.6890 | 25 (23.6) | 39 (20.7) | 0.5710 |
| Current drinking | 20 (33.3) | 33 (38.4) | 0.5333 | 10 (9.4) | 22 (11.7) | 0.5488 |
| Systolic blood pressure, mmHg | 140.0 ± 24.2 | 138.0 ± 22.5 | 0.6073 | 152.2 ± 19.8 | 148.9 ± 21.3 | 0.1947 |
| HbA1c, % | 10.3 ± 2.3 | 9.8 ± 2.2 | 0.1774 | 8.9 ± 2.2 | 9.2 ± 2.1 | 0.1747 |
| ≥7.0 | 47 (94.0) | 70 (90.9) | 0.7389 | 83 (78.3) | 162 (86.2) | 0.0822 |
| HDL-C, mmol/L | 1.17 ± 0.36 | 1.09 ± 0.29 | 0.1886 | 1.41 ± 0.42 | 1.08 ± 0.31 | <0.0001 |
| <1.00 in male or <1.30 in female | 35 (58.3) | 55 (64.0) | 0.4920 | 23 (21.7) | 115 (61.2) | <0.0001 |
| LDL-C, mmol/L | 3.13 ± 0.96 | 3.56 ± 1.04 | 0.0118 | 2.97 ± 0.80 | 2.68 ± 0.97 | 0.0062 |
| ≥2.60 | 42 (70.0) | 72 (83.7) | 0.0486 | 81 (76.4) | 103 (54.8) | 0.0002 |
| Fasting C-peptide, ng/ml | - | - | - | 1.12 (0.81–1.55) | 1.75 (1.26–2.34) | 0.0002 |
| Antidiabetic agents | 60 (100.0) | 83 (96.5) | 0.2688 | 101 (95.3) | 176 (93.6) | 0.6147 |
| Diabetic nephropathy | 23 (38.3) | 21 (24.4) | 0.0714 | 51 (48.1) | 87 (46.3) | 0.7619 |
| Diabetic retinopathy | 14 (23.3) | 17 (19.8) | 0.6042 | 26 (25.2) | 58 (31.2) | 0.2868 |
TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HbA1c, glycated hemoglobin; LMUFAH, Liaoning Medical University First Affiliated Hospital; SAHODMU, the Second affiliated hospital of Dalian Medical University.
Data are mean ± standard deviation, median (IQR), or n (%).
P values were derived from independent-samples Student t test for normally distributed variables, Mann-Whitney U test for skewed distributions, Chi-square test (or fisher test if appropriate) for categorical variables. P < 0.05 was defined as statistically significant.