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. 2021 Jun 7;22(2):591. doi: 10.3892/ol.2021.12852

Figure 5.

Figure 5.

Downregulation of miR-4491 inhibited cell proliferation and induced cell apoptosis by targeting TRIM7 in non-small cell lung cancer cell lines. Effect of si-TRIM7 was rescued by miR-4491 inhibitor and resulted in (A and B) decreased proliferation and (C and D) increased apoptosis of A549 and NCI-H1650 cells. ***P<0.001 vs. miR-NC + si-control. &P<0.05, &&P<0.01 and &&&P<0.001 vs. miR-4491 inhibitor + si-control. miR, microRNA; TRIM7, tripartite motif containing 7; NC, negative control; si, small interfering.