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. 2021 Jun 7;22(11):6137. doi: 10.3390/ijms22116137

Figure 10.

Figure 10

Schematic diagram showing the beneficial effects of Pangasius hypophthalmus fish skin hydrolysates (fsCH) on UV-B radiation-damaged skin of SKH-1 hairless mice. As depicted, fsCH attenuated dermal wrinkle formation in fibroblasts and epidermal water loss in keratinocytes. The symbol ⟘ indicates sites of inhibition manifested by fsCH and the symbol → indicates activation. UV-B, ultraviolet-B; MMP, matrix metalloproteinases; AQP3, aquaporin 3; HAS2, hyaluronic acid synthase 2; HYAL1, hyaluronidase 1.