Table 2.

Codon and amino acid changes in POLE-mutated cases.

Case	Initial Biopsy Histology	Codon Change	Amino Acid Change	Mutation Events	Total Events	Mutation Event Percent
49	EIN	857C > G	Pro286Arg	8	120	6.7
50	EIN	857C > G	Pro286Arg	37	159	23.3
51	EIN	1231G > T	Val411Leu	12	132	9.1
52	EIN	857C > G	Pro286Arg	3	54	5.6

Abbreviations: EIN: endometrial intraepithelial neoplasia; Val: valine; Leu: leucine; Pro: proline; Arg: arginine.