Table 1.

Gene expression changes in MDA-MB231 breast cancer cells exposed to 5mM CdCl₂ for 96 h.

Gene	Protein Product	Up↑ Down↓	Fold Changes
HSPA5	Endoplasmic reticulum chaperone BiP	↓	54.2
HSPA8	Heat shock cognate 71 kDa protein	↓	4.9
HSPB1	Heat shock protein β-1	↑	8.7
HSPD1	60 kDa heat shock protein, mitochondrial	↓	2
HSP90AB1	Heat shock protein HSP 90-β	↓	2.57
TRAP1	Heat shock protein 75 kDa, mitochondrial	↓	9.5
MT1A	Metallothionein-1A	↑	2.34
MT1F	Metallothionein-1F	↑	3.65
MT1G	Metallothionein-1G	↓	18.8
COX2	Cytochrome c oxidase subunit 2	↓	3
COX4	Cytochrome c oxidase subunit 4	↓	1.9
BCL2	Bcl-2	↓	53
WAF1	Cyclin-dependent kinase inhibitor 1	↑	10.4
DAPK	Death-associated protein kinase-1	↑	55
RIPK1	Receptor-interacting protein 1	↑	undetectable in control
CASP1	Caspase-1	↑	106
CASP2	Caspase-2	↑	3
CASP6	Caspase-6	↑	31.3
CASP7	Caspase-7	↑	15
CASP8	Caspase-8	↑	9.25
CASP9	Caspase-9	↑	4.7
MAPK14	Mitogen-activated protein kinase p38 α	↓	8
MAPK11	Mitogen-activated protein kinase p38 β	↓	4
MAPK12	Mitogen-activated protein kinase p38 γ	↑	7
AEG1	Astrocyte elevated gene-1 protein	↓	8.5
PLP2	Proteolipid protein 2	↑	2
FOS	Proto-oncogene c-Fos	↓	3.2
JUN	Proto-oncogene c-Jun	↓	3.5