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. 2021 Jun 5;13(11):2818. doi: 10.3390/cancers13112818

Table 2.

List of studies exhibiting biosynthesized gold NPs and their anticancer activity.

Plant Plant Part Used Morphology/Size (nm) Exposure Time Cancer Type/Cell Line Used IC50 Value Ref.
Azadirachta indica Leaf Spherical, triangular, hexagonal 48 h Cervical cancer/HeLa No toxicity [133]
Genipa americana L. Fruit Spherical/30.4 ± 14.9 48 h Cervical cancer/HeLa No toxicity [134]
Dracocephalum kotschyi Leaf Spherical/11 24 h, 48 h, 72 h Cervical cancer/HeLa 152.16 µg/mL [135]
Zataria multiflora Leaf Pentagon, triangular/10–50 48 h Cervical cancer/HeLa 100 µg/m [132]
Areca catechu Nut Spherical/22.2 24 h Cervical cancer/HeLa 25.17 µg/mL [136]
Mimosa pudica Leaf Spherical/12 24 h, 48 h Breast cancer/MCF-7 6 µg/mL [121]
Musa paradisiaca (banana) Stem Spherical/30 24 h Breast cancer/MCF-7 Low toxicity [122]
Antigonon letopus Hook. and Arn. Aerial part Spherical, triangular/13–28 48 h Breast cancer/MCF-7 257.8 μg/mL [123]
Corallina officinalis Aqueous Extract Spherical/14.6 NA Breast Cancer/MCF-7 NA [125]
Phoenix dactylifera flower Near spherical/95 24 h Breast Cancer/MCF-7 4.76 μg/mL [126]
Vites vinefera Aqueous Extract Spherical/20–45 24 h Breast Cancer/HBL- 100 NA [127]
Acalypha indica Leaf Spherical/20–30 30 min Breast Cancer/MDA- MB-231 NA [124]
Alternanthera bettzickiana Leaf Spherical and aggregated/80–120 10 min Lung Cancer/A549 NA [128]
Sesuvium portulacastrum Leaf Mostly Spherical/35–40 0–8 h Lung Cancer/A549 14 μg/mL [129]
Star anise (Illicium verum) Pod Hexagonal, triangular/20–150 48 h Lung cancer/A549 Low toxicity [130]
Star anise (Illicium verum) Pod Hexagonal, triangular/20–50 48 h Lung cancer/A549 Low toxicity at 200 nM [130]
Musa paradisiaca (banana) Stem Spherical/30 24 h Kidney cancer/HEK293 >80 nM [122]
Ficus religiosa Bark Spherical/20–30 24 h Kidney cancer/HEK 293 No toxicity [138]
Hibiscus sabdariffa Leaf, stem Near spherical/10–60 48 h Kidney cancer/HEK 293 2 ng/mL [137]
Couroupita guianensis Flower Polydispersed, spherical, triangular, tetragonal/7–48 5 min Leukaemia/HL-60 NA [139]
Cajanus cajan Seed coat Spherical/9–41 24 h Liver cancer/HepG2 6 µg/mL [140]