Table 3.
List of studies exhibiting biosynthesized zinc NPs and their anticancer activity.
| Plant | Plant Part Used | Morphology/Size (nm) | Exposure Time | Cancer Type/Cell Line | IC50 Value | Ref. |
|---|---|---|---|---|---|---|
| Abutilon indicum | Leaf | Spherical/35.2 ± 2.3 | 2–3 h | Lung cancer/Calu-6 | 9.34 ± 0.4 μg/mL | [143] |
| Calotropis gigantea | Leaf | Spherical/30–35 | 3 h | Lung cancer/Calu-6 | 11.6 ± 0.9 μg/mL | [144] |
| Laurus nobilis | Leaf | Hexagonal/47.27 | 4 h | Lung cancer/A549 | 11.3 ± 0.9 μg/mL | [142] |
| Cannabis sativa | Leaf | Hexagonal/40 ± 1.5 | 3 h | Lung cancer/A549 | 18.3 ± 1.3 μg/mL | [145] |
| Calotropis procera | Leaf | Spherical/5–40 | 4 h | Lung cancer/A549 | 15.2 ± 1.6 μg/mL | [146] |
| Withania Somnifera | Leaf | Hexagonal/51.34 | 2–3 h | Leukemia/WEHI-3 | 12.4 ± 1.6 μg/mL | [147] |
| Sargassum muticum | Leaf | Spherical/22.5 ± 3.5 | 3–4 h | Leukemia/WEHI-3 | 2.25 ± 0.4 μg/mL | [148] |
| Tabernaemontana divaricate | Leaf | Spherical/36 ± 5 | 3 h | Breast cancer/MCF-7 | 30.6 μg/mL | [149] |
| Tabernaemontana divaricate | Leaf | Spherical/36 ± 5 | 4 h | Breast cancer/MCF-7 | 30.6 μg/mL | [150] |
| Tabernaemontana | Leaf | Spherical/36 ± 5 | 3–4 h | Breast cancer/MCF-7 | 30 μg/mL | [151] |
| Borassus flabellifer | Leaf | Spherical/55 | 3 h | Breast cancer/MCF-7 | 0.125 μg/mL | [152] |
| Embelia ribes | Root | Spherical/130–150 | 2 h | Breast cancer/MCF-7 | 9.62 ± 1.9 μg/mL | [153] |
| Saccharum officinarum | Juice | Spherical/19 ± 2.3 | 4 h | Breast cancer/MCF-7 | 16.7 ± 0.5 μg/mL | [106] |
| Anabaena variabilis | Phyco-bili pigment | Spherical/42 ± 3 | 5–6 h | Breast cancer/MCF-7 | 16.5 1.6 μg/mL | [154] |
| Atropa belladonna | Leaf | Hexagonal/34 ± 3.2 | 2 h | Breast cancer/MCF-7 | 12 ±0.9 μg/mL | [160] |