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Predicted and experimental value of response at the optimized conditions.
| Dependent Variables | Symbol | Constraints |
|---|---|---|
| Vesicular size (nm) | Y1 | Minimize |
| EE (%) | Y2 | Maximize |
| Flux (%) | Y3 | Maximize |
| Response | Predicted values | Experimental values |
| Y1 (nm) | 140 ± 1.9 | 145.6 ± 2.3 |
| Y2 (%) | 71.1 ± 2.4 | 72.9 ± 2.1 |
| Y3 (µg/cm2·h) | 0.531 ± 0.04 | 0.513 ± 0.03 |
