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. 2021 Jun 7;22(11):6126. doi: 10.3390/ijms22116126
AA amino-acid
aFGF acidic fibroblast growth factor
ALK1-7 activin receptor-like kinases
Ang angiopoietin
ANGPTL angiopoietin-like protein
ApoE apolipoprotein E
AQP4 aquaporin 4
BBB blood–brain barrier
BTB blood–brain tumor barrier
BTRE brain tumor-related edema
bFGF basic fibroblast growth factor
BM bone marrow
BMDCs bone-marrow-derived cells
BMP bone morphogenetic protein
CNS central nervous system
CXCL chemokine C-X-C motif ligand
CXCR CXC chemokine receptor
CCL chemokine C-C motif ligand
CCR CC chemokine receptor
DcR-3 decoy receptor 3
DR-3 death receptor 3
EC endothelial cells
ECM extracellular matrix
EGF epidermal growth factor
eNOS endothelial nitric oxide synthase
ERK extracellular-signal-regulated kinase
FGF fibroblast growth factor
GBM glioblastoma multiforme
HGF hepatocyte growth factor
HGG high-grade gliomas
HIF-1 hypoxia-inducible factor 1
IDH isocitrate dehydrogenase
IFN interferon
IL interleukin
IL-12 interleukin-12
IMG intussusceptive microvascular growth
ICP intracranial pressure
ITSs interstitial/intervascular tissue structures
KDR kinase domain receptor
LGG low-grade gliomas
LOH loss of heterozygosity
LPS lipopolysaccharides
MIP-1 monocyte chemoattractant protein-1
MMPs matrix metalloproteinases
MT-MMP membrane-type matrix metalloproteinase
NK natural killer
NO nitric oxide
NRP1 neuropilin
NVU neurovascular units
PDGF platelet-derived growth factor
PlGF placental growth factor
PrGBM primary GBM
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2
ScGBM secondary GBM
sNRP1 soluble form of neuropilin
TAMs tumor infiltrating macrophages
TEK endothelial-specific receptor tyrosine kinase
TGF-α transforming growth factor alpha
TGF-β transforming growth factor-beta
Tie-1 tyrosine kinase receptors with immunoglobulin-like and EGF-like domain 1
TIMP tissue inhibitor of metalloproteinases
TL1A TNF-like ligand 1A
TMZ temozolomide
TNFSF15 TNF superfamily member 15
TNF-α tumor necrosis factor alpha
TβRIII type III TGF-β co-receptor
uPA urokinase-type plasminogen activator
VEGF vascular endothelial growth factor
VEGFR-1 receptor 1 for VEGF
VEGFR-2 VEGF receptor-2
VEGI vascular endothelial growth inhibitor
VM vascular mimicry
vSMCs vascular smooth muscle cells
WHO World Health Organization