Table 3.

Results of the 250 mcg ACTH stimulation test.

Parameter	Baseline	End of Study	Difference	p Value
ACTH, pg/mL
Baseline	17.6 (6.7–23.4)	18.0 (11.1–24.1)	0.1 (−4.1–5.9)	0.638
Cortisol, mcg/dL
Baseline	13 (10.3–15.8)	12.3 (8.9–19.3)	0.1 (−2.5–1.7)	0.975
30 min	30 (25.2–32.4)	28.1 (23.9–37.2	0.9 (−2.6–4.3)	0.552
60 min	33.9 (29.9–38)	31.1 (28.4–41.1)	−0.1 (−2.4–3.1)	0.701
Aldosterone, ng/dL
Baseline	13.9 (6.7–40.4)	7.9 (5.6–14.5)	−2.9 (−37.6–-0.3)	0.036
30 min	25.2 (14.6–124.3)	16.9 (12.0–32.6)	−3.4 (−116.3–−1.1)	0.008
60 min	21.3 (15.2–78.6)	16.8 (12.2–29.8)	3.9 (−36.5–1.1)	0.064
PRA, ng/mL/h
Baseline	1.5 (0.8–3.6)	1.5 (0.8–3.6)	−0.2 (−1.0–0.6)	0.65
30 min	1.2 (0.3–3.8)	1.2 (0.3–3.8)	0.3 (−0.2–1.1)	0.328
60 min	0.8 (0.6–3)	0.8 (0.6–3)	−0.2 (−0.7–0.8)	0.972

Abbreviations: ACTH, adrenocorticotropic hormone; PRA, plasma renin activity; Q1, first quartile; Q3, third quartile.