. 2021 Jun 7;22(11):6147. doi: 10.3390/ijms22116147

Table 3.

Genotype and Allele Frequencies of MALAT1 rs3200401 (C/T) and PVT1 rs13255292 (C/T) in CRC and Non-CRC.

MALAT1 rs3200401 (C/T) (n = 280, Adjusted Analysis)
Model	Genotype	Non-CRC (n = 140)	CRC (n = 140)	Adjusted OR (95% CI)	p Value ^a	AIC ^a	BIC ^a
Codominant	CC	59 (42.1%)	31 (22.1%)	1	<0.0001	362.2	380.4
	CT	63 (45%)	62 (44.3%)	1.82 (1.03–3.23)
	TT	18 (12.9%)	47 (33.6%)	5.12 (2.49–10.51)
Dominant	CC	59 (42.1%)	31 (22.1%)	1	<0.0001	369.8	384.4
Dominant	CT-TT	81 (57.9%)	109 (77.9%)	2.53 (1.48–4.32)	<0.0001	369.8	384.4
Recessive	CC-CT	122 (87.1%)	93 (66.4%)	1	<0.0001	364.5	379
Recessive	TT	18 (12.9%)	47 (33.6%)	3.60 (1.92–6.77)	<0.0001	364.5	379
Overdominant	CC-TT	77 (55%)	78 (55.7%)	1	0.83	381.8	396.3
Overdominant	CT	63 (45%)	62 (44.3%)	0.95 (0.58–1.54)	0.83	381.8	396.3
Allelic	C	181 (65%)	124 (44%)	2.21 (1.55–3.14)	<0.0001	360.9	375.4
Allelic	T	99 (35%)	156 (56%)	2.21 (1.55–3.14)	<0.0001	360.9	375.4
PVT1 rs13255292 (C/T) (n = 280, Adjusted Analysis)
Model	Genotype	Non-CRC (n = 140)	CRC (n = 140)	OR (95% CI)	p Value	AIC	BIC
Codominant	CC	47 (33.6%)	64 (45.7%)	1	0.1	379.3	397.4
	CT	75 (53.6%)	62 (44.3%)	0.59 (0.35–1.00)
	TT	18 (12.9%)	14 (10%)	0.55 (0.24–1.24)
Dominant	CC	47 (33.6%)	64 (45.7%)	1	0.034	377.3	391.9
Dominant	CT-TT	93 (66.4%)	76 (54.3%)	0.59 (0.36–0.96)
Recessive	CC-CT	122 (87.1%)	126 (90%)	1	0.42	381.2	395.7
Recessive	TT	18 (12.9%)	14 (10%)	0.73 (0.34–1.57)
Overdominant	CC-TT	65 (46.4%)	78 (55.7%)	1	0.12	379.4	393.9
Overdominant	CT	75 (53.6%)	62 (44.3%)	0.68 (0.42–1.10)	0.12	379.4	393.9
Allelic	C	169 (60%)	190 (68%)	0.70 (0.49–1.01)	0.048	377.9	392.5
Allelic	T	111 (40%)	90 (32%)	0.70 (0.49–1.01)	0.048	377.9	392.5

Values are expressed as number (percentage). ^a adjusted for age and sex in a logistic regression model. p < 0.05 means statistical significance. AIC: Akaike’s Information Criteria, BIC: Bayesian Information Criteria.