Table 5.
Diagnostic accuracy of the studied markers between CRC and non-CRC groups.
| Marker | Cutoff | AUC | p Value | Sensitivity | Specificity | PPV | NPV | 95% CI |
|---|---|---|---|---|---|---|---|---|
| MALAT1 | >23.71-fold | 0.907 | <0.0001 | 82% | 88% | 90% | 78% | 0.8435 to 0.9707 |
| PVT1 | >13.96-fold | 0.848 | <0.0001 | 90% | 70% | 80% | 84% | 0.7641 to 0.9316 |
| miRNA-101 | <0.28-fold | 0.686 | 0.0049 | 62% | 67% | 72% | 56% | 0.5697 to 0.8015 |
| miRNA-186 | <0.20-fold | 0.702 | 0.0028 | 54% | 80% | 78% | 55% | 0.5861 to 0.8172 |
| E-Cadherin | <3.81 ng/mL | 0.864 | <0.0001 | 76% | 90% | 91% | 73% | 0.7837 to 0.9442 |
AUC—area under the curve, (PPV)—positive predictive value, (NPV)—negative predictive value, (CI)—confidence interval. p < 0.05 means statistical significance.