Table 2.
Hierarchical additive hazards model and Cox proportional hazards model regressions for the association of race and survival, stratified by center-level characteristics, 2010 - 2017.
| Unadjusted | Clinical1 | Clinical + Socioeconomic2 | Clinical + Socioeconomic + Center3 | |||||
|---|---|---|---|---|---|---|---|---|
| Survival Difference per 100,000 PY (95% CI) | Hazard Ratio (95% CI) | Survival Difference per 100,000 PY (95% CI) | Hazard Ratio (95% CI) | Survival Difference per 100,000 PY (95% CI) | Hazard Ratio (95% CI) | Survival Difference per 100,000 PY (95% CI) | Hazard Ratio (95% CI) | |
| Overall | 3.30 (2.07, 4.53) | 1.24 (1.13, 1.37) | 3.68 (2.47, 4.89) | 1.27 (1.16, 1.38) | 3.25 (2.03, 4.47) | 1.23 (1.12, 1.34) | 3.07 (1.82, 4.32) | 1.21 (1.12, 1.31) |
| Transplant volume | ||||||||
| Low | 2.31 (−1.79, 6.41) | 1.16 (0.89, 1.50) | 3.47 (−0.61, 7.55) | 1.22 (0.96, 1.55) | 2.87 (−1.21, 6.95) | 1.18 (0.93, 1.49) | 2.58 (−1.52, 6.68) | 1.14 (0.90, 1.46) |
| Medium | 2.44 (0.05, 4.83) | 1.18 (1.01, 1.37) | 2.27 (−0.04, 4.54) | 1.16 (1.00, 1.35) | 1.70 (−0.57, 3.97) | 1.12 (0.96, 1.30) | 1.45 (−0.84, 3.74) | 1.09 (0.94, 1.28) |
| High | 3.75 (2.22, 5.28) | 1.28 (1.14, 1.44) | 4.22 (2.72, 5.72) | 1.31 (1.18, 1.46) | 3.86 (2.36, 5.36) | 1.28 (1.15, 1.43) | 3.74 (2.22, 5.26) | 1.27 (1.15, 1.39) |
| Proportion of black patients at center | ||||||||
| Low | 4.64 (−0.52, 9.79) | 1.36 (1.02, 1.80) | 4.08 (−0.51, 8.67) | 1.30 (0.95, 1.78) | 3.69 (−0.90, 8.28) | 1.27 (0.93, 1.73) | 3.62 (−0.97, 8.21) | 1.26 (0.92, 1.72) |
| Medium | 2.63 (0.47, 4.79) | 1.20 (1.05, 1.37) | 3.11 (1.03, 5.19) | 1.22 (1.07, 1.39) | 2.70 (0.60, 4.80) | 1.19 (1.04, 1.36) | 2.79 (0.69, 4.89) | 1.19 (1.04, 1.37) |
| High | 3.41 (1.79, 5.03) | 1.25 (1.12, 1.39) | 3.66 (2.06, 5.26) | 1.26 (1.14, 1.39) | 3.17 (1.56, 4.78) | 1.22 (1.11, 1.35) | 3.16 (1.55, 4.77) | 1.22 (1.09, 1.34) |
| SRTR tier | ||||||||
| 1 | 5.00 (0.67, 9.33) | 1.37 (1.14, 1.65) | 4.75 (0.44, 9.06) | 1.34 (1.11, 1.62) | 4.77 (0.42, 9.12) | 1.33 (1.11, 1.60) | 4.67 (0.32, 9.02) | 1.32 (1.09, 1.58) |
| 2 | 4.97 (2.58, 7.36) | 1.35 (1.14, 1.61) | 4.99 (2.60, 7.38) | 1.35 (1.14, 1.61) | 4.58 (2.19, 6.97) | 1.31 (1.10, 1.57) | 4.44 (2.03, 6.85) | 1.30 (1.09, 1.54) |
| 3 | 2.75 (0.61, 4.89) | 1.21 (1.06, 1.37) | 3.05 (0.89, 5.21) | 1.22 (1.07, 1.38) | 2.64 (0.48, 4.80) | 1.19 (1.04, 1.35) | 2.49 (0.31, 4.67) | 1.17 (1.03, 1.33) |
| 4 | 2.00 (−0.43, 4.43) | 1.15 (0.98, 1.34) | 2.41 (−0.02, 4.84) | 1.16 (1.00, 1.36) | 2.02 (−0.41, 4.54) | 1.13 (0.97, 1.32) | 1.73 (−0.72, 4.18) | 1.11 (0.95, 1.29) |
| 5 | 2.36 (−0.84, 5.55) | 1.18 (0.93, 1.50) | 3.27 (0.08, 6.46) | 1.25 (1.01, 1.56) | 2.84 (−0.38, 6.04) | 1.22 (0.98, 1.52) | 2,61 (−0.62, 5.84) | 1.20 (0.97, 1.49) |
| Geographic region | ||||||||
| Northeast | 4.16 (1.40, 6.92) | 1.29 (1.13, 1.49) | 4.06 (1.30, 6.82) | 1.26 (1.09, 1.46) | 3.72 (0.96, 6.48) | 1.23 (1.06, 1.43) | 3.62 (0.84, 6.40) | 1.22 (1.06, 1.41) |
| Midwest | 3.15 (0.07, 6.23) | 1.23 (1.03, 1.47) | 2.88 (1.36, 5.62) | 1.20 (1.01, 1.42) | 2.32 (−0.42, 5.06) | 1.15 (0.97, 1.37) | 2.18 (−0.58, 4.94) | 1.14 (0.95, 1.36) |
| South | 2.98 (1.33, 4.64) | 1.22 (1.07, 1.40) | 3.70 (2.07, 5.33) | 1.28 (1.13, 1.45) | 3.38 (1.74, 5.02) | 1.25 (1.10, 1.42) | 3.28 (1.62, 4.94) | 1.24 (1.11, 1.39) |
| West | 2.62 (−0.17, 6.89) | 1.20 (0.95, 1.52) | 2.50 (−1.62, 6.62) | 1.18 (0.96, 1.45) | 2.23 (−1.89, 6.35) | 1.15 (0.94, 1.42) | 2.14 (−1.98, 6.26) | 1.14 (0.93, 1.41) |
Adjusted for age, year of transplant, sex, MELD at transplant, underlying cause of disease, recipient medical condition at transplant, body mass index (BMI), donor risk index (DRI), portal vein thrombosis (PVT), history of diabetes, and dialysis at transplant.
Adjusted for age, year of transplant, sex, MELD at transplant, underlying cause of disease, recipient medical condition at transplant, body mass index (BMI), donor risk index (DRI), portal vein thrombosis (PVT), history of diabetes, dialysis at transplant, educational attainment, zip-code income, and primary payer.
Adjusted for age, year of transplant, sex, MELD at transplant, underlying cause of disease, recipient medical condition at transplant, body mass index (BMI), donor risk index (DRI), portal vein thrombosis (PVT), history of diabetes, dialysis at transplant, educational attainment, zip-code income, primary payer, and center-level characteristics.