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. 2021 May 27;64(11):7296–7311. doi: 10.1021/acs.jmedchem.0c01313

Figure 11.

Figure 11

Pharmacokinetics data of compound 6 in the CD1 mouse following a single intravenous (IV) and oral administration (PO). Dose: 3 mg/kg, IV; 10 mg/kg, PO. Formulation vehicle: 5% v/v NMP: 5% v/v solute HS-15 and 90% v/v normal saline. The measured plasma free fraction used to calculate unbound concentration was 0.00744 ± 0.001. NA = not applicable.