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DEX induces co-localization of NeuN and LC3B in the cerebral cortex of rats with CIR. Immunofluorescence staining was used to detect co-expression of NeuN and LC3B. Scale bar, 50 µm. Magnification, ×400 (n=6). *P<0.05, **P<0.01 vs. Sham; #P<0.05, ##P<0.01 vs. CIR; &P<0.05, &&P<0.01 vs. anta-NC; ^P<0.05 vs. DEX. LC3B, microtubule-associated proteins 1A/1B light chain 3B; CIR, cerebral ischemia-reperfusion; DEX, dexmedetomidine; anta, antagomir; miR, microRNA; NC, negative control.
