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Toxicities induced by afatinib (n = 35)
| n (%) | ||||
|---|---|---|---|---|
| Adverse events | All grades | Grade 1 | Grade 2 | ≥Grade 3 |
| Diarrhea | 33 (94.3) | 12 (34.3) | 12 (34.3) | 9 (25.7) |
| Rash/acne | 27 (77.1) | 17 (48.6) | 7 (20) | 3 (8.6) |
| Stomatitis | 20 (57.1) | 16 (45.7) | 2 (5.6) | 2 (5.7) |
| Paronychia | 21 (60) | 15 (42.9) | 5 (14.3) | 1 (2.9) |
| Elevation of AST/ALT | 4 (11.4) | 3 (8.6) | 0 | 1 (2.9) |
