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. 2021 Jun 1;10(3):651–661. doi: 10.1093/toxres/tfab041

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PVT1 overexpression diminished the inhibitory effect of CurTn on AAA formation by regulating miR-26a/KLF4/PI3K/AKT axis. (A) Western blotting measured the expressions of PI3K, p-PI3K, AKT and p-AKT. (B) VSMCs migration was assessed using the transwell assay. Gene expressions (C) and protein levels (D) of inflammatory cytokines were detected by qPCR or western blotting. (E) VSMCs pyroptosis was measured using flow cytometry, and the quantitive data were calculated accordingly. ^*P < .05, ^*^*P < .01, ^*^*^*P < .001.