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. 2021 May 31;12:681492. doi: 10.3389/fphar.2021.681492

TABLE 2.

Contributions to changes in pharmaceutical spending by 2-year periods, overall and by sector (%).

2010–2011 vs. 2012–2013 2012–2013 vs. 2014–2015 2014–2015 vs. 2016–2017 2016–2017 vs. 2018–2019 Annual average (Change)
Total Relative increment −0.74 7.82 16.40 16.09 4.9 (100)
New drugs 1.58 2.19 2.69 1.70 1.0 (21)
Continued drugs −2.22 5.81 13.77 14.67 4.0 (81)
 Price (P) −16.34 −6.51 −2.19 −3.04 −3.5 (−71)
 Mixed effect in the main active ingredient −1.36 −1.24 −1.09 −0.22 −0.5 (−10)
 Quantity (Q) 15.48 13.56 17.05 17.92 8 (162)
Abandoned drugs −0.10 −0.17 −0.06 −0.27 −0.1 (−2)
Inpatient relative increment −6.05 1.92 10.77 10.89 2.2 (100)
New drugs 0.62 3.27 1.68 2.64 1.0 (47)
Continued drugs −6.48 −1.16 9.21 8.48 1.3 (57)
 Price (P) −15.62 −7.45 −4.14 −3.58 −3.8 (−176)
 Mixed effect in the main active ingredient −0.67 −0.45 −0.93 0.01 −0.3 (−12)
 Quantity (Q) 9.81 6.74 14.28 12.05 5.4 (245)
Abandoned drugs −0.19 −0.19 −0.12 −0.23 −0.1 (−4)
Outpatient Relative increment 0.31 8.91 17.38 16.94 5.4 (100)
New drugs 2.09 2.01 4.61 1.56 1.3 (24)
Continued drugs −1.58 7.10 12.82 15.69 4.3 (78)
 Price (P) −16.80 −6.31 −1.58 −2.94 −3.5 (−63)
 Mixed effect in the main active ingredient −1.50 −1.40 −1.19 −0.24 −0.5 (−10)
 Quantity (Q) 16.72 14.81 15.59 18.87 8.2 (152)
Abandoned drugs −0.20 −0.21 −0.05 −0.31 −0.1 (−2)

Changes were calculated as the annual average.