TABLE 1.

Rats’ body composition parameters.

	9 days				21 days
	CTRL	COLD	HYPO	COHY	CTRL	COLD	HYPO	COHY
	n = 14	n = 15	n = 11	n = 16	n = 14	n = 13	n = 11	n = 14
BW (Δ%)	24.8 ± 1.2	22.6 ± 1.7	18.7 ± 1.5*	16.5 ± 1.6**#	41.7 ± 3.2	48.9 ± 1.9*	37.7 ± 2.6##	36.1 ± 1.9##
Muscle (GAS+TA)/ 100 g BW	1.68 ± 0.01	1.64 ± 0.03	1.80 ± 0.09**##	1.74 ± 0.03	2.62 ± 0.04	3.08 ± 0.0**	3.35 ± 0.11**##	3.01 ± 0.06**$$
PAT/BW (mg/g)	8.98 ± 0.41	8.13 ± 0.37	7.81 ± 0.46	8.47 ± 0.62	10.00 ± 0.39	10.07 ± 0.37	8.38 ± 0.38*#	10.3 ± 0.43$
BAT/BW (mg/g)	1.31 ± 0.08	1.73 ± 0.10**	0.76 ± 0.04**##	1.43 ± 0.04#$$	1.12 ± 0.06	1.38 ± 0.05*	0.89 ± 0.03*##	1.33 ± 0.27*$$
Diaphragm/BW (mg/g)	1.93 ± 0.05	1.90 ± 0.05	1.80 ± 0.04	1.74 ± 0.13	1.81 ± 0.08	1.82 ± 0.05	1.83 ± 0.09	2.03 ± 0.10
Heart/BW (mg/g)	3.35 ± 0.04	3.34 ± 0.06	3.48 ± 0.10	3.43 ± 0.07	3.37 ± 0.08	3.41 ± 0.10	3.40 ± 0.07	3.59 ± 0.07
Right ventricle/total heart (%)	24.4 ± 0.8	25.0 ± 0.7	28.3 ± 1.4*#	24.5 ± 0.5$	25.6 ± 1.2	26.3 ± 1.2	28.8 ± 0.8	26.4 ± 0.9

Data are presented as mean ± standard error. BW, body weight; GAS, gastrocnemius muscle; TA, tibialis anterior muscle; PAT, perigonadal adipose tissue; BAT, brown adipose tissue. CTRL, control; COLD, intermittent cold; HYPO, intermittent hypoxia; COHY, intermittent cold + hypoxia. Statistically significant differences are indicated as follows: *p < 0.05 vs. CTRL, **p < 0.001 vs. CTRL, ^#p < 0.05 vs. COLD, ^##p < 0.001 vs. COLD, ^$p < 0.05 vs. HYPO, ^$$p < 0.001 vs. HYPO.