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. 2021 Jun 14;14:160. doi: 10.1186/s12920-021-01009-7

Table 1.

Clinical and biological findings of patients with KIN in families A and Z

Patient No Sexe AN AERSD Smoking Personal history Cause of renal examination HMG TR Death Initial creatinine (µmol/l) eGFR ml/min/1.73m2 Cytolisis Cholestasis VST KB Liver Biopsy
Family A IV-2 M 36 36 No 0 Convulsion 0 Yes No 900 9.9 Yes Yes No No
IV-7 M 39 43 Yes Appendectomy Donor check up 0 Yes Yes 161 69.4 No Yes

Yes

K + 

Yes

K-

IV-11 M 26 29 No 0 Donor Check up 0 No Yes 197 53.38 Yes Yes No No
IV-12 M 32 38 No Urethritis Donor Check up 0 No No 141 65.9 Yes Yes

Yes

K + 

No
Family Z II-2 M 31 36 No 0 Fortuitously 0 Yes Yes 1000 ND No No No No
II-3 M 25 33 No Epilepsy and visceral leishmaniasis Donor check up 0 No No 200 ND No No

Yes

K + 

Yes

K-

AN, age at the time of the discovery of nephropathy; AERSD, Age at the time of the end of renal stage disease; HMG, hepatomegaly; TR, transplantation; eGFR, estimated glomerular filtration rate; VST, viral serology test; KB, Kidney biopsy; K, Karyomegaly; + , present; -, absent; ND, no data