Table 2.

Eligibility criteria

Inclusion criteria	Exclusion criteria
1. Studies comparing at least two interventional groups	1. Human studies
2. In vivo animal models of TBI or ischemic stroke or hemorrhagic stroke (ICH or SAH)	2. In vitro studies
3. RBC transfusion in at least one interventional group	3. Non-mammals used as animal models
4. Different transfusion strategy or no transfusion or any other intervention as a comparator	4. Transfusion before cerebral injury is induced
5. Any study outcome

TBI traumatic brain injury, ICH intracerebral hemorrhage, SAH subarachnoid hemorrhage, RBC red blood cell