Table 2.

Details of seven selected genes

N	Gene symbol	Full name	Function
1	HMMR	hyaluronan mediated motility receptor	the driver of tumor progression, plays a important role in the modulation of motor activities and the maintenance of genome stability.
2	SPP1	secreted phosphoprotein 1	The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix
3	FN1	fibronectin 1	Fibronectin 1 (FN1) is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, metastasis, and implicated in various biochemical processes.
4	CCNB1	cyclin B1	an important regulator in cell cycle machinery, is a monitoring protein in mitosis and expressed primarily in G2/M phase which is critical for controlling the cell cycle at the G2/M (mitosis) transition
5	CXCL8	C-X-C motif chemokine ligand 8	a chemokine that acts as an important multifunctional cytokine to modulate tumour proliferation, invasion and migration in an autocrine or paracrine manner.
6	MAD2L1	mitotic arrest deficient 2 like 1	a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate
7	CCNA2	cyclin A2	The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle.